Cargando…

Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection

Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.

Detalles Bibliográficos
Autor principal: Valenzuela, Nicole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729816/
https://www.ncbi.nlm.nih.gov/pubmed/36384088
http://dx.doi.org/10.1016/j.xcrm.2022.100809