Mendelian randomization and pathway analysis demonstrate shared genetic associations between lupus and coronary artery disease

Coronary artery disease (CAD) is a leading cause of death in patients with systemic lupus erythematosus (SLE). Despite clinical evidence supporting an association between SLE and CAD, pleiotropy-adjusted genetic association studies are limited and focus on only a few common risk loci. Here, we ident...

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Detalles Bibliográficos
Autores principales: Kain, Jessica, Owen, Katherine A., Marion, Miranda C., Langefeld, Carl D., Grammer, Amrie C., Lipsky, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729823/
https://www.ncbi.nlm.nih.gov/pubmed/36334592
http://dx.doi.org/10.1016/j.xcrm.2022.100805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729823/
https://www.ncbi.nlm.nih.gov/pubmed/36334592
http://dx.doi.org/10.1016/j.xcrm.2022.100805

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