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Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

Glucagon analogs show promise as components of next-generation, multi-target, anti-obesity therapeutics. The biology of chronic glucagon treatment, in particular, its ability to induce energy expenditure and weight loss, remains poorly understood. Using a long-acting glucagon analog, G108, we demons...

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Detalles Bibliográficos
Autores principales: Hope, David C.D., Hinds, Charlotte E., Lopes, Tatiana, Vincent, Matthew L., Shrewsbury, Jed V., Yu, Arthur T.C., Davies, Iona, Scott, Rebecca, Jones, Ben, Murphy, Kevin G., Minnion, James S., Sardini, Alessandro, Carling, David, Lutz, Thomas A., Bloom, Stephen R., Tan, Tricia M.M., Owen, Bryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729826/
https://www.ncbi.nlm.nih.gov/pubmed/36384093
http://dx.doi.org/10.1016/j.xcrm.2022.100810