Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytes

Mechanisms underlying anti-diabetic effects of GLP1 analogs remain incompletely understood. We observed that in prediabetic humans exenatide treatment acutely induces interleukin-6 (IL-6) secretion by monocytes and IL-6 in systemic circulation. We hypothesized that GLP1 analogs signal through IL-6 i...

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Detalles Bibliográficos
Autores principales: Gutierrez, Absalon D., Gao, Zhanguo, Hamidi, Vala, Zhu, Liang, Saint Andre, Karla Bermudez, Riggs, Kayla, Ruscheinsky, Monika, Wang, Hongyu, Yu, Yongmei, Miller, Charles, Vasquez, Hernan, Taegtmeyer, Heinrich, Kolonin, Mikhail G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729831/
https://www.ncbi.nlm.nih.gov/pubmed/36384099
http://dx.doi.org/10.1016/j.xcrm.2022.100813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729831/
https://www.ncbi.nlm.nih.gov/pubmed/36384099
http://dx.doi.org/10.1016/j.xcrm.2022.100813

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