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P53 maintains gallid alpha herpesvirus 1 replication by direct regulation of nucleotide metabolism and ATP synthesis through its target genes

P53, a well-known tumor suppressor, has been confirmed to regulate the infection of various viruses, including chicken viruses. Our previous study observed antiviral effect of p53 inhibitor Pifithrin-α (PFT-α) on the infection of avian infectious laryngotracheitis virus (ILTV), one of the major avia...

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Detalles Bibliográficos
Autores principales: Xu, Li, Chen, Zhijie, Zhang, Yu, Cui, Lu, Liu, Zheyi, Li, Xuefeng, Liu, Shengwang, Li, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729838/
https://www.ncbi.nlm.nih.gov/pubmed/36504811
http://dx.doi.org/10.3389/fmicb.2022.1044141