Structure-based virtual screening identified novel FOXM1 inhibitors as the lead compounds for ovarian cancer

Ovarian cancer (OC) is a gynecological tumor with possibly the worst prognosis, its 5-year survival rate being only 47.4%. The first line of therapy prescribed is chemotherapy consisting of platinum and paclitaxel. The primary reason for treatment failure is drug resistance. FOXM1 protein has been f...

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Detalles Bibliográficos
Autores principales: Zhou, Zi-Ying, Han, Xiao-Yang, Sun, Lian-Qi, Li, Si-Yan, Xue, Si-Tu, Li, Zhuo-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729839/
https://www.ncbi.nlm.nih.gov/pubmed/36505747
http://dx.doi.org/10.3389/fchem.2022.1058256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729839/
https://www.ncbi.nlm.nih.gov/pubmed/36505747
http://dx.doi.org/10.3389/fchem.2022.1058256

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