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FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast

FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its nonessentiality and multifunctionality. Here, we show that FKBP12 promotes the utilization of seri...

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Detalles Bibliográficos
Autores principales: Sasaki, Mayuki, Nishimura, Shinichi, Yashiroda, Yoko, Matsuyama, Akihisa, Kakeya, Hideaki, Yoshida, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730122/
https://www.ncbi.nlm.nih.gov/pubmed/36505930
http://dx.doi.org/10.1016/j.isci.2022.105659