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FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast
FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its nonessentiality and multifunctionality. Here, we show that FKBP12 promotes the utilization of seri...
Autores principales: | Sasaki, Mayuki, Nishimura, Shinichi, Yashiroda, Yoko, Matsuyama, Akihisa, Kakeya, Hideaki, Yoshida, Minoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730122/ https://www.ncbi.nlm.nih.gov/pubmed/36505930 http://dx.doi.org/10.1016/j.isci.2022.105659 |
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