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Radiolabeled albumin through S(N)Ar of cysteines as a potential pretargeting theranostic agent

Human serum albumin (HSA) has been shown to be a promising tumor targeting vector and target for generating theranostics by bioconjugation. Unstable chemical conjugation to HSA via a cysteine (Cys34) by reversible Michael additions is most commonly applied for this purpose. Herein, we describe utili...

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Detalles Bibliográficos
Autores principales: Fischer, Niklas H., Lopes van den Broek, Sara I., Herth, Matthias M., Diness, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730197/
https://www.ncbi.nlm.nih.gov/pubmed/36540259
http://dx.doi.org/10.1039/d2ra06406e