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Radiolabeled albumin through S(N)Ar of cysteines as a potential pretargeting theranostic agent
Human serum albumin (HSA) has been shown to be a promising tumor targeting vector and target for generating theranostics by bioconjugation. Unstable chemical conjugation to HSA via a cysteine (Cys34) by reversible Michael additions is most commonly applied for this purpose. Herein, we describe utili...
Autores principales: | Fischer, Niklas H., Lopes van den Broek, Sara I., Herth, Matthias M., Diness, Frederik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730197/ https://www.ncbi.nlm.nih.gov/pubmed/36540259 http://dx.doi.org/10.1039/d2ra06406e |
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