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Selinexor, a selective inhibitor of nuclear export, inhibits human neutrophil extracellular trap formation in vitro
Neutrophils are central players in the innate immune system. To protect against invading pathogens, neutrophils can externalize chromatin to create neutrophil extracellular traps (NETs). While NETs are critical to host defense, they also have deleterious effects, and dysregulation of NETs formation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730241/ https://www.ncbi.nlm.nih.gov/pubmed/36506529 http://dx.doi.org/10.3389/fphar.2022.1030991 |