Selinexor, a selective inhibitor of nuclear export, inhibits human neutrophil extracellular trap formation in vitro

Neutrophils are central players in the innate immune system. To protect against invading pathogens, neutrophils can externalize chromatin to create neutrophil extracellular traps (NETs). While NETs are critical to host defense, they also have deleterious effects, and dysregulation of NETs formation...

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Detalles Bibliográficos
Autores principales: Baron, Szilvia, Rashal, Tami, Vaisman, Dmitry, Elhasid, Ronit, Shukrun, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730241/
https://www.ncbi.nlm.nih.gov/pubmed/36506529
http://dx.doi.org/10.3389/fphar.2022.1030991

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