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Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages

BACKGROUND: Colony-stimulating factor 1 receptor (CSF1R), a classic tyrosine kinase receptor, has been identified as a proto-oncogene in multiple cancers. The CSF1/CSF1R axis is essential for the survival and differentiation of M2-phenotype tumor-associated macrophages (M2 TAMs). However, we found h...

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Detalles Bibliográficos
Autores principales: Zhu, Mingxuan, Bai, Liangliang, Liu, Xiaoxia, Peng, Shaoyong, Xie, Yumo, Bai, Hong, Yu, Huichuan, Wang, Xiaolin, Yuan, Ping, Ma, Rui, Lin, Jinxin, Wu, Linping, Huang, Meijin, Li, Yingjie, Luo, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730427/
https://www.ncbi.nlm.nih.gov/pubmed/36600555
http://dx.doi.org/10.1136/jitc-2022-005610