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Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt
[Image: see text] A-9758 is an inverse agonist of retinoic acid-related orphan receptor γt with well-characterized in vitro and in vivo anti-inflammatory activity. A chromatography-free decagram-scale synthesis of this compound was developed to support pre-clinical research activities. This route wa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730458/ https://www.ncbi.nlm.nih.gov/pubmed/36506123 http://dx.doi.org/10.1021/acsomega.2c06060 |