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Mutational Insight into Allosteric Regulation of Kir Channel Activity

[Image: see text] Potassium (K(+)) channels are regulated in part by allosteric communication between the helical bundle crossing, or inner gate, and the selectivity filter, or outer gate. This network is triggered by gating stimuli. In concert, there is an allosteric network which is a conjugated s...

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Detalles Bibliográficos
Autores principales: Yekefallah, Maryam, Rasberry, Carver A., van Aalst, Evan J., Browning, Holley P., Amani, Reza, Versteeg, Derek B., Wylie, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730464/
https://www.ncbi.nlm.nih.gov/pubmed/36506180
http://dx.doi.org/10.1021/acsomega.2c04456