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Novel 5-(Arylideneamino)-1H-Benzo[d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies

[Image: see text] A novel series of multifunctional benzimidazoles has been reported as potent inhibitors of α-glucosidase. The procedure relies on the synthesis of 5-amino-1H-benzo[d]imidazole-2-thiol 5 via the multistep reaction through 2-nitroaniline 1, benzene-1,2-diamine 2, 1H-benzo[d]imidazole...

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Detalles Bibliográficos
Autores principales: Ali, Sardar, Ali, Mumtaz, Khan, Ajmal, Ullah, Saeed, Waqas, Muhammad, Al-Harrasi, Ahmed, Latif, Abdul, Ahmad, Manzoor, Saadiq, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730482/
https://www.ncbi.nlm.nih.gov/pubmed/36506132
http://dx.doi.org/10.1021/acsomega.2c03854