Cargando…
Novel 5-(Arylideneamino)-1H-Benzo[d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies
[Image: see text] A novel series of multifunctional benzimidazoles has been reported as potent inhibitors of α-glucosidase. The procedure relies on the synthesis of 5-amino-1H-benzo[d]imidazole-2-thiol 5 via the multistep reaction through 2-nitroaniline 1, benzene-1,2-diamine 2, 1H-benzo[d]imidazole...
Autores principales: | Ali, Sardar, Ali, Mumtaz, Khan, Ajmal, Ullah, Saeed, Waqas, Muhammad, Al-Harrasi, Ahmed, Latif, Abdul, Ahmad, Manzoor, Saadiq, Muhammad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730482/ https://www.ncbi.nlm.nih.gov/pubmed/36506132 http://dx.doi.org/10.1021/acsomega.2c03854 |
Ejemplares similares
-
Synthesis, Bioactivity Assessment, and Molecular Docking of Non-sulfonamide
Benzimidazole-Derived N-Acylhydrazone Scaffolds
as Carbonic Anhydrase-II Inhibitors
por: Saadiq, Muhammad, et al.
Publicado: (2021) -
Mercaptobenzimidazole-Based
1,3-Thaizolidin-4-ones
as Antidiabetic Agents: Synthesis, In Vitro α-Glucosidase
Inhibition Activity, and Molecular Docking Studies
por: Khan, Sher Ali, et al.
Publicado: (2022) -
Neurologically Potent Molecules from Crataegus oxyacantha; Isolation, Anticholinesterase Inhibition, and Molecular Docking
por: Ali, Mumtaz, et al.
Publicado: (2017) -
Synthesis of novel coumarin–hydrazone hybrids as α-glucosidase inhibitors and their molecular docking studies
por: Tariq, Hafiza Zara, et al.
Publicado: (2023) -
Bio-Oriented Synthesis of Novel Polyhydroquinoline
Derivatives as α-Glucosidase Inhibitor for Management
of Diabetes
por: Talab, Faiz, et al.
Publicado: (2023)