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Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process

[Image: see text] The polymorphic control of active pharmaceutical ingredients (APIs) is a major challenge in the manufacture of medicines. Crystallization methods that use supercritical carbon dioxide as an antisolvent can create unique solid forms of APIs, with a particular tendency to generate me...

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Detalles Bibliográficos
Autores principales: Cañellas, Fidel Méndez, Verma, Vivek, Kujawski, Jacek, Geertman, Robert, Tajber, Lidia, Padrela, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730483/
https://www.ncbi.nlm.nih.gov/pubmed/36506150
http://dx.doi.org/10.1021/acsomega.2c05259