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Pro-resolving and anti-arthritic properties of the MC(1) selective agonist PL8177

BACKGROUND: Melanocortins are peptides endowed with anti-inflammatory and pro-resolving activities. Many of these effects are mediated by the Melanocortin receptor 1 (MC(1)) as reported in several experimental settings. As such, MC(1) can be a viable target for the development of new therapies that...

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Detalles Bibliográficos
Autores principales: Garrido-Mesa, Jose, Thomas, Bethan Lynne, Dodd, John, Spana, Carl, Perretti, Mauro, Montero-Melendez, Trinidad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730523/
https://www.ncbi.nlm.nih.gov/pubmed/36505403
http://dx.doi.org/10.3389/fimmu.2022.1078678