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Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions

Introduction: Altered signaling or function of acetylcholine (ACh) has been reported in various neurological diseases, including Alzheimer’s disease, Tourette syndrome, epilepsy among others. Many neurons that release ACh also co-transmit the neurotransmitter gamma-aminobutyrate (GABA) at synapses i...

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Detalles Bibliográficos
Autores principales: Goral, R. Oliver, Harper, Kathryn M., Bernstein, Briana J., Fry, Sydney A., Lamb, Patricia W., Moy, Sheryl S., Cushman, Jesse D., Yakel, Jerrel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730538/
https://www.ncbi.nlm.nih.gov/pubmed/36505727
http://dx.doi.org/10.3389/fnbeh.2022.1067409