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Identifying novel proteins underlying schizophrenia via integrating pQTLs of the plasma, CSF, and brain with GWAS summary data

BACKGROUND: Schizophrenia (SCZ) is a chronic and severe mental illness with no cure so far. Mendelian randomization (MR) is a genetic method widely used to explore etiologies of complex traits. In the current study, we aimed to identify novel proteins underlying SCZ with a systematic analytical appr...

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Detalles Bibliográficos
Autores principales: Gu, Xiaojing, Dou, Meng, Su, Weiming, Jiang, Zheng, Duan, Qingqing, Cao, Bei, Chen, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730613/
https://www.ncbi.nlm.nih.gov/pubmed/36482464
http://dx.doi.org/10.1186/s12916-022-02679-5