Cargando…
Identifying novel proteins underlying schizophrenia via integrating pQTLs of the plasma, CSF, and brain with GWAS summary data
BACKGROUND: Schizophrenia (SCZ) is a chronic and severe mental illness with no cure so far. Mendelian randomization (MR) is a genetic method widely used to explore etiologies of complex traits. In the current study, we aimed to identify novel proteins underlying SCZ with a systematic analytical appr...
Autores principales: | Gu, Xiaojing, Dou, Meng, Su, Weiming, Jiang, Zheng, Duan, Qingqing, Cao, Bei, Chen, Yongping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730613/ https://www.ncbi.nlm.nih.gov/pubmed/36482464 http://dx.doi.org/10.1186/s12916-022-02679-5 |
Ejemplares similares
-
A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)
por: Melzer, David, et al.
Publicado: (2008) -
Breeding drought-resistant crops: G×E interactions, proteomics and pQTLS
por: Kosová, Klára, et al.
Publicado: (2019) -
GWAS with principal component analysis identify QTLs associated with main peanut flavor-related traits
por: Zhang, Hui, et al.
Publicado: (2023) -
Coanalysis of GWAS with eQTLs reveals disease-tissue associations
por: Kang, Hyunseok Peter, et al.
Publicado: (2012) -
Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores
por: Privé, Florian, et al.
Publicado: (2022)