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METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

OBJECTIVE: N6-methyladenosine (m6A) RNA methylation is involved in governing the mechanism of tumor progression. We aimed to excavate the biological role and mechanism of the m6A methyltransferase METTL3 in cholangiocarcinoma (CCA). METHODS: METTL3 expression was determined by database and tissue mi...

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Detalles Bibliográficos
Autores principales: Cai, Jingli, Cui, Zheng, Zhou, Jingyi, Zhang, Bosen, Lu, Ruiqi, Ding, Youcheng, Hu, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730622/
https://www.ncbi.nlm.nih.gov/pubmed/36476503
http://dx.doi.org/10.1186/s12935-022-02809-2