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Clinical application of RUBCN/SESN2 mediated inhibition of autophagy as biomarkers of diabetic kidney disease

BACKGROUND: Deregulated autophagy in diabetes has been a field of many experimental studies recently. Impaired autophagy in diabetic kidneys orchestrates every step of diabetic nephropathy (DN) pathogenesis. This study aimed to evaluate three autophagy regulators; RUBCN, mTOR, and SESN2 as clinicall...

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Detalles Bibliográficos
Autores principales: Watany, Mona M., El-Horany, Hemat E., Elhosary, Marwa M., Elhadidy, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730641/
https://www.ncbi.nlm.nih.gov/pubmed/36476132
http://dx.doi.org/10.1186/s10020-022-00580-8