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Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells

BACKGROUND: ACTN4 is an actin-binding protein involved in many cellular processes, including cancer development. High ACTN4 expression is often associated with a poor prognosis. However, it has been identified as a positive marker for platinum-based adjuvant chemotherapy for non-small cell lung canc...

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Detalles Bibliográficos
Autores principales: Kriger, Daria, Novitskaya, Ksenia, Vasileva, Giomar, Lomert, Ekaterina, Aksenov, Nikolai D., Barlev, Nikolai A., Tentler, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730676/
https://www.ncbi.nlm.nih.gov/pubmed/36476259
http://dx.doi.org/10.1186/s13062-022-00354-6