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The accumulation of muscle RING finger-1 in regenerating myofibers: Implications for muscle repair in immune-mediated necrotizing myopathy

BACKGROUND: Muscle RING finger-1 (MuRF-1) plays a key role in the degradation of skeletal muscle proteins. We hypothesize the involvement of MuRF-1 in immune-mediated necrotizing myopathy (IMNM). METHODS: Muscle biopsies from patients with IMNM (n = 37) were analyzed and compared to biopsies from pa...

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Detalles Bibliográficos
Autores principales: Yang, Meng-Ge, Zhang, Qing, Wang, Hong, Ma, Xue, Ji, Suqiong, Li, Yue, Xu, Li, Bi, Zhuajin, Bu, Bitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730696/
https://www.ncbi.nlm.nih.gov/pubmed/36504647
http://dx.doi.org/10.3389/fneur.2022.1032738