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Reaction Mechanism of Ancestral l-Lys α-Oxidase from Caulobacter Species Studied by Biochemical, Structural, and Computational Analysis

[Image: see text] The flavin-dependent amine oxidase superfamily contains various l-amino acid oxidases (LAAOs) bearing different substrate specificities and enzymatic properties. LAAOs catalyze the oxidation of the α-amino group of l-amino acids (L-AAs) to produce imino acids and H(2)O(2). In this...

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Detalles Bibliográficos
Autores principales: Motoyama, Tomoharu, Yamamoto, Yuta, Ishida, Chiharu, Hasebe, Fumihito, Kawamura, Yui, Shigeta, Yasuteru, Ito, Sohei, Nakano, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730747/
https://www.ncbi.nlm.nih.gov/pubmed/36506213
http://dx.doi.org/10.1021/acsomega.2c06334