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Molecular Mechanics Simulations and Experimental Investigation of the Effect of Tadalafil on Various Inflammatory Pain Mediators

[Image: see text] Purpose: Tadalafil’s exact analgesic mechanism is still unclear. The current study aimed to elucidate this mechanism in an inflammatory pain model. Methods: Computer-assisted simulation docking experiments were carried out to assess the binding of tadalafil to different ligands. Th...

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Detalles Bibliográficos
Autores principales: Domiati, Souraya, Abd El Galil, Khaled, Ragab, Hanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730770/
https://www.ncbi.nlm.nih.gov/pubmed/36506154
http://dx.doi.org/10.1021/acsomega.2c04761