Epigenomic signatures associated with spontaneous and replication stress-induced DNA double strand breaks

Common fragile sites (CFSs) are specific regions of all individuals’ genome that are predisposed to DNA double strand breaks (DSBs) and undergo subsequent rearrangements. CFS formation can be induced in vitro by mild level of DNA replication stress, such as DNA polymerase inhibition or nucleotide po...

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Detalles Bibliográficos
Autores principales: Kodali, Sravan, Meyer-Nava, Silvia, Landry, Stephen, Chakraborty, Arijita, Rivera-Mulia, Juan Carlos, Feng, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730818/
https://www.ncbi.nlm.nih.gov/pubmed/36506300
http://dx.doi.org/10.3389/fgene.2022.907547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730818/
https://www.ncbi.nlm.nih.gov/pubmed/36506300
http://dx.doi.org/10.3389/fgene.2022.907547

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