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Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation
Recent advances in DNA sequencing technologies are revealing a large individual variability of the human genome. Our capacity to establish genotype-phenotype correlations in such large-scale is, however, limited. This task is particularly challenging due to the multifunctional nature of many protein...
Autores principales: | Pacheco-Garcia, Juan Luis, Cagiada, Matteo, Tienne-Matos, Kelly, Salido, Eduardo, Lindorff-Larsen, Kresten, L. Pey, Angel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730889/ https://www.ncbi.nlm.nih.gov/pubmed/36504709 http://dx.doi.org/10.3389/fmolb.2022.1063620 |
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