Development of Fluorinated NP-59: A Revival of Cholesterol Use Imaging with PET

Imaging of cholesterol use is possible with the (131)I scintiscanning/SPECT agent NP-59. This agent provided a noninvasive measure of adrenal function and steroid synthesis. However, iodine isotopes resulted in poor resolution, manufacturing challenges, and high radiation dosimetry to patients that...

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Detalles Bibliográficos
Autores principales: Brooks, Allen F., Winton, Wade P., Stauff, Jenelle, Arteaga, Janna, Henderson, Bradford, Niedbala, Jeremy, Scott, Peter J.H., Viglianti, Benjamin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Clinical Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730927/
https://www.ncbi.nlm.nih.gov/pubmed/35483964
http://dx.doi.org/10.2967/jnumed.122.263864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9730927/
https://www.ncbi.nlm.nih.gov/pubmed/35483964
http://dx.doi.org/10.2967/jnumed.122.263864

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