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Integrated spatial analysis of gene mutation and gene expression for understanding tumor diversity in formalin-fixed paraffin-embedded lung adenocarcinoma

INTRODUCTION: A deeper understanding of intratumoral heterogeneity is essential for prognosis prediction or accurate treatment plan decisions in clinical practice. However, due to the cross-links and degradation of biomolecules within formalin-fixed paraffin-embedded (FFPE) specimens, it is challeng...

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Detalles Bibliográficos
Autores principales: Yamazaki, Miki, Hosokawa, Masahito, Matsunaga, Hiroko, Arikawa, Koji, Takamochi, Kazuya, Suzuki, Kenji, Hayashi, Takuo, Kambara, Hideki, Takeyama, Haruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731154/
https://www.ncbi.nlm.nih.gov/pubmed/36505794
http://dx.doi.org/10.3389/fonc.2022.936190