MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors

MYC is dysregulated in >50% of cancers, but direct targeting of MYC has been clinically unsuccessful. Targeting downstream MYC effector pathways represents an attractive alternative. MYC regulates alternative mRNA splicing, but the mechanistic links between MYC and the splicing machinery in cance...

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Detalles Bibliográficos
Autores principales: Urbanski, Laura, Brugiolo, Mattia, Park, SungHee, Angarola, Brittany L., Leclair, Nathan K., Yurieva, Marina, Palmer, Phil, Sahu, Sangram Keshari, Anczuków, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731204/
https://www.ncbi.nlm.nih.gov/pubmed/36417849
http://dx.doi.org/10.1016/j.celrep.2022.111704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731204/
https://www.ncbi.nlm.nih.gov/pubmed/36417849
http://dx.doi.org/10.1016/j.celrep.2022.111704

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