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Case report: Optimized ruxolitinib-based therapy in an infant with familial hemophagocytic lymphohistiocytosis type 3

Familial hemophagocytic lymphohistiocytosis (FHL) is a rare and fatal autosomal recessive immune disorder characterized by uncontrolled activation of T and NK cells, macrophages, and overproduction of inflammatory cytokines. Early hematopoietic cell transplantation (HCT) is required for long-term su...

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Detalles Bibliográficos
Autores principales: Niizato, Daiki, Isoda, Takeshi, Mitsuiki, Noriko, Kaneko, Shuya, Tomomasa, Dan, Kamiya, Takahiro, Takagi, Masatoshi, Imai, Kohsuke, Kajiwara, Michiko, Shimizu, Masaki, Morio, Tomohiro, Kanegane, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731208/
https://www.ncbi.nlm.nih.gov/pubmed/36505485
http://dx.doi.org/10.3389/fimmu.2022.977463