Trypanosoma brucei Mitochondrial DNA Polymerase POLIB Contains a Novel Polymerase Domain Insertion That Confers Dominant Exonuclease Activity

[Image: see text] Trypanosoma brucei and related parasites contain an unusual catenated mitochondrial genome known as kinetoplast DNA (kDNA) composed of maxicircles and minicircles. The kDNA structure and replication mechanism are divergent and essential for parasite survival. POLIB is one of three...

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Detalles Bibliográficos
Autores principales: Delzell, Stephanie B., Nelson, Scott W., Frost, Matthew P., Klingbeil, Michele M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731263/
https://www.ncbi.nlm.nih.gov/pubmed/36399653
http://dx.doi.org/10.1021/acs.biochem.2c00392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731263/
https://www.ncbi.nlm.nih.gov/pubmed/36399653
http://dx.doi.org/10.1021/acs.biochem.2c00392

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