Adenylate Kinase-Catalyzed Reactions of AMP in Pieces: Specificity for Catalysis at the Nucleoside Activator and Dianion Catalytic Sites

[Image: see text] The pressure to optimize the enzymatic rate acceleration for adenylate kinase (AK)-catalyzed phosphoryl transfer has led to the evolution of an induced-fit mechanism, where the binding energy from interactions between the protein and substrate adenosyl group is utilized to drive a...

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Detalles Bibliográficos
Autores principales: Fernandez, Patrick L., Richard, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731266/
https://www.ncbi.nlm.nih.gov/pubmed/36413937
http://dx.doi.org/10.1021/acs.biochem.2c00531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731266/
https://www.ncbi.nlm.nih.gov/pubmed/36413937
http://dx.doi.org/10.1021/acs.biochem.2c00531

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