Cargando…

Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome

Lack of FMR1 protein results in fragile X syndrome (FXS), which is the most common inherited intellectual disability syndrome and serves as an excellent model disease to study molecular mechanisms resulting in neuropsychiatric comorbidities. We compared the transcriptomes of human neural progenitors...

Descripción completa

Detalles Bibliográficos
Autores principales: Talvio, Karo, Minkeviciene, Rimante, Townsley, Kayla G., Achuta, Venkat Swaroop, Huckins, Laura M., Corcoran, Padraic, Brennand, Kristen J., Castrén, Maija L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731341/
https://www.ncbi.nlm.nih.gov/pubmed/36506088
http://dx.doi.org/10.3389/fcell.2022.1034679