Conformational sampling of CMT-2D associated GlyRS mutations

During protein synthesis, aminoacyl-tRNA synthetases covalently link amino acids with their cognate tRNAs. Amino acid mutations in glycyl-tRNA synthetase can disrupt protein synthesis and lead to a neurological disorder known as Charcot-Marie-Tooth disease type 2D (CMT-2D). Several studies employing...

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Detalles Bibliográficos
Autores principales: Childers, Matthew Carter, Regnier, Michael, Bothwell, Mark, Smith, Alec S.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731397/
https://www.ncbi.nlm.nih.gov/pubmed/36504507
http://dx.doi.org/10.1016/j.brain.2022.100054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731397/
https://www.ncbi.nlm.nih.gov/pubmed/36504507
http://dx.doi.org/10.1016/j.brain.2022.100054

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