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Whole blood RNA-seq demonstrates an increased host immune response in individuals with cystic fibrosis who develop nontuberculous mycobacterial pulmonary disease

BACKGROUND: Individuals with cystic fibrosis have an elevated lifetime risk of colonization, infection, and disease caused by nontuberculous mycobacteria. A prior study involving non-cystic fibrosis individuals reported a gene expression signature associated with susceptibility to nontuberculous myc...

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Detalles Bibliográficos
Autores principales: Prieto, Miguel Dario, Jang, Jiah, Franciosi, Alessandro N., Av-Gay, Yossef, Bach, Horacio, Tebbutt, Scott J., Quon, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731410/
https://www.ncbi.nlm.nih.gov/pubmed/36480571
http://dx.doi.org/10.1371/journal.pone.0278296