Triggering of lymphocytes by CD28, 4-1BB, and PD-1 checkpoints to enhance the immune response capacities

Tumor infiltrating lymphocytes (TILs) usually become exhausted and dysfunctional owing to chronic contact with tumor cells and overexpression of multiple inhibitor receptors. Activation of TILs by targeting the inhibitory and stimulatory checkpoints has emerged as one of the most promising immunothe...

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Detalles Bibliográficos
Autores principales: Kaviani, Elina, Hosseini, Ahmad, Mahmoudi Maymand, Elham, Ramzi, Mani, Ghaderi, Abbas, Ramezani, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731445/
https://www.ncbi.nlm.nih.gov/pubmed/36480493
http://dx.doi.org/10.1371/journal.pone.0275777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731445/
https://www.ncbi.nlm.nih.gov/pubmed/36480493
http://dx.doi.org/10.1371/journal.pone.0275777

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