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Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers
Oncogenic kinase inhibitors show short-lived responses in the clinic due to high rate of acquired resistance. We previously showed that pharmacologically exploiting oncogene-induced proteotoxic stress can be a viable alternative to oncogene-targeted therapy. Here, we performed extensive analyses of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731458/ https://www.ncbi.nlm.nih.gov/pubmed/36480552 http://dx.doi.org/10.1371/journal.pone.0256788 |