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Inference of B cell clonal families using heavy/light chain pairing information

Next generation sequencing of B cell receptor (BCR) repertoires has become a ubiquitous tool for understanding the antibody-mediated immune response: it is now common to have large volumes of sequence data coding for both the heavy and light chain subunits of the BCR. However, until the recent devel...

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Detalles Bibliográficos
Autores principales: Ralph, Duncan K., Matsen, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731466/
https://www.ncbi.nlm.nih.gov/pubmed/36441808
http://dx.doi.org/10.1371/journal.pcbi.1010723