Expansion of CD8(+) T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors

INTRODUCTION: Lassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear. METHODS: We investigated Lassa virus specific CD8(+) T cell responses in 93 LF survivors. Peripheral blood mo...

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Detalles Bibliográficos
Autores principales: LaVergne, Stephanie M., Sakabe, Saori, Momoh, Mambu, Kanneh, Lansana, Bond, Nell, Garry, Robert F., Grant, Donald S., de la Torre, Juan Carlos, Oldstone, Michael B. A., Schieffelin, John S., Sullivan, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731491/
https://www.ncbi.nlm.nih.gov/pubmed/36441765
http://dx.doi.org/10.1371/journal.pntd.0010882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731491/
https://www.ncbi.nlm.nih.gov/pubmed/36441765
http://dx.doi.org/10.1371/journal.pntd.0010882

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