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Harmol hydrochloride dihydrate induces autophagy in neuro cells and promotes the degradation of α‐Syn by Atg5/Atg12‐dependent pathway

Harmol hydrochloride dihydrate (HHD) is a novel alkaloid salt of the natural β‐carboline harmol, which is isolated from Peganum harmala L. Here, we studied whether HHD could induce autophagy in neuro cells and investigated the underlying molecular mechanism. After incubation with HHD, the number of...

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Detalles Bibliográficos
Autores principales: Abulimiti, Gulinuer, Zeng, Jianghua, Aimaiti, Mutalifu, Lei, Xiuying, Mi, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731543/
https://www.ncbi.nlm.nih.gov/pubmed/36514773
http://dx.doi.org/10.1002/fsn3.3031