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Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules

The mitoribosome regulates cellular energy production, and its dysfunction is associated with aging. Inhibition of the mitoribosome can be caused by off-target binding of antimicrobial drugs and was shown to be coupled with a bilateral decreased visual acuity. Previously, we reported mitochondria-sp...

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Detalles Bibliográficos
Autores principales: Itoh, Yuzuru, Singh, Vivek, Khawaja, Anas, Naschberger, Andreas, Nguyen, Minh Duc, Rorbach, Joanna, Amunts, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731571/
https://www.ncbi.nlm.nih.gov/pubmed/36480258
http://dx.doi.org/10.7554/eLife.77460