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Machine Learning Guides Peptide Nucleic Acid Flow Synthesis and Sequence Design

Peptide nucleic acids (PNAs) are potential antisense therapies for genetic, acquired, and viral diseases. Efficiently selecting candidate PNA sequences for synthesis and evaluation from a genome containing hundreds to thousands of options can be challenging. To facilitate this process, this work lev...

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Detalles Bibliográficos
Autores principales: Li, Chengxi, Zhang, Genwei, Mohapatra, Somesh, Callahan, Alex J., Loas, Andrei, Gómez‐Bombarelli, Rafael, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731686/
https://www.ncbi.nlm.nih.gov/pubmed/36270977
http://dx.doi.org/10.1002/advs.202201988