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Human Islet Amyloid Polypeptide (hIAPP) Protofibril‐Specific Antibodies for Detection and Treatment of Type 2 Diabetes

Type 2 diabetes mellitus (T2D) is a major public health concern and is characterized by sustained hyperglycemia due to insulin resistance and destruction of insulin‐producing β cells. One pathological hallmark of T2D is the toxic accumulation of human islet amyloid polypeptide (hIAPP) aggregates. Mo...

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Detalles Bibliográficos
Autores principales: Bortoletto, Angelina S., Graham, W. Vallen, Trout, Gabriella, Bonito‐Oliva, Alessandra, Kazmi, Manija A., Gong, Jing, Weyburne, Emily, Houser, Brandy L., Sakmar, Thomas P., Parchem, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731688/
https://www.ncbi.nlm.nih.gov/pubmed/36257905
http://dx.doi.org/10.1002/advs.202202342