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Human Islet Amyloid Polypeptide (hIAPP) Protofibril‐Specific Antibodies for Detection and Treatment of Type 2 Diabetes
Type 2 diabetes mellitus (T2D) is a major public health concern and is characterized by sustained hyperglycemia due to insulin resistance and destruction of insulin‐producing β cells. One pathological hallmark of T2D is the toxic accumulation of human islet amyloid polypeptide (hIAPP) aggregates. Mo...
Autores principales: | Bortoletto, Angelina S., Graham, W. Vallen, Trout, Gabriella, Bonito‐Oliva, Alessandra, Kazmi, Manija A., Gong, Jing, Weyburne, Emily, Houser, Brandy L., Sakmar, Thomas P., Parchem, Ronald J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731688/ https://www.ncbi.nlm.nih.gov/pubmed/36257905 http://dx.doi.org/10.1002/advs.202202342 |
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