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Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation

Optogenetic genome engineering is a powerful technology for high‐resolution spatiotemporal genetic manipulation, especially for in vivo studies. It is difficult to generate stable transgenic animals carrying a tightly regulated optogenetic system, as its long‐term expression induces high background...

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Detalles Bibliográficos
Autores principales: Li, Huiying, Wu, Yingyin, Qiu, Yuhao, Li, Xinru, Guan, Yuting, Cao, Xiya, Liu, Meizhen, Zhang, Dan, Huang, Sijie, Lin, Longnian, Hui, Lijian, Ma, Xueyun, Liu, Mingyao, Zhang, Xueli, Wang, Liren, Li, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731692/
https://www.ncbi.nlm.nih.gov/pubmed/36266974
http://dx.doi.org/10.1002/advs.202201352