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Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α

BACKGROUND: Sodium chloride (NaCl) reabsorption in the cortical thick ascending limb (cTAL) is regulated by opposing effects. Nitric oxide (NO) inhibits NaCl reabsorption while 8-iso-prostaglandin-F2α (8-iso-PGF2α) stimulates it. Their interaction has not been evaluated in the cTAL. Because 8-iso-PG...

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Detalles Bibliográficos
Autores principales: Cabral, Pablo D., Silva, Guillermo B., Baigorria, Sandra T., Juncos, Luis I., Ajayi, Ebenezer I. O., García, Néstor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731782/
https://www.ncbi.nlm.nih.gov/pubmed/35977909
http://dx.doi.org/10.23876/j.krcp.21.243